comparison of corneal and anterior segment parameters between pentacam and galilei

baradaran rafii ar, md; motevasseli t, md*; yazdizadeh f, md; ansari sh, md; karimian f, md; sadoughi mm, md; kiani h ocular tissue engineering research center, shahid beheshti university of medical sciences, tehran, iran * corresponding author: [email protected] purpose: to compare anterior segment indices measured by two scheimpflug camera; galilei and pentacam. methods: in this observational case series, myopic patients scheduled for refractive surgery underwent corneal and anterior segment analyses using pentacam (single scheimpflug camera) and galilei (dual scheimpflug camera). analyzed parameters included anterior and posterior best-fit spheres (bfs), axial curvature, true corneal power, central corneal thickness (cct), anterior chamber (ac) depth, ac volume, ac angle and pupil diameter. statistical analysis was performed using paired t- test and bland-altman plots. results:  the study comprised 176 eyes of 88 patients. the mean radius of the anterior bfs was 7.79 ± 0.34 mm measured with pentacam and 7.75 ± 0.39 mm measured with galilei (r=0.877,p<0.001), and the mean radius of posterior bfs was 6.42 ± 0.32 mm and 6.47 ± 0.38 mm, respectively, (r=0.879,p<0.001). anterior axial curvature was 43.8 ± 1.9 d with pentacam and 43.8± 2.4 d with galilei (r=0.905,p<0.003). posterior axial curvature was 6.3 ± 0.3 d and 6.3 ± 0.4 d, respectively (r=0.873, p<0.001). true corneal power was 43.9 ± 1.9 d with pentacam and 43.5± 2.3 d with galilei (r=0.909,p<0.001). cct was 537±44 µm with pentacam and 553±51 µm with galilei (r=0.796,p<0.001). anterior chamber depth was 3.29±0.4 mm and 3.3±0.38 mm (r=0.85, p<0.001), anterior chamber volume was 207±50 mm³ and 129±39 mm³ (p=0.004), anterior chamber angle was 39.7±9.2 degree and 54.2±5.2 degree (p=0.051), respectively. average pupil diameter was 3.91±1.77 mm with pentacam and 3.34±0.89 mm with galilei (p=0.007). there was a significant correlation between all measured parameters except for cct, ac volume, ac angle, and pupil diameter. conclusion: there is a significant agreement between galilei and pentacam scheimpflug analyzers in most of the measured indices. however, the correlation can be low in some parameters. therefore, these two devices cannot be used interchangeably.